#36 - Solving Health Using AI | Max Marchione, Superpower

You're going to have a choice of injection this morning. I came down with one of the worst sore throats I had in my life. What did I do? I injected the

my life. What did I do? I injected the snapper one.

>> What I've at least seen is everything I've started doing that everyone laughs at and calls crazy. Several years later starts to become mainstream.

>> That burns a little bit.

Super excited to interview uh Max Mchioni. All right, let's start off with

Mchioni. All right, let's start off with uh you injecting me with whatever those three vials are.

>> You're going to have a choice of injection this morning. Um, so every Friday our team does a Friday breakfast.

Uh, which means we inject each other because we we think it's fun and we think that many of these compounds also improve human human uh potential. Uh, so

there there are three different ones here we can play around with. One is

thyus. Now for one, I never get sick anymore because every time I'm about to get sick, I use this and I don't get sick. My sore throat disappears. The

sick. My sore throat disappears. The

second is NAD+, which is used for cellular energy, longevity, and just like energy dayto-day. Um, if you take this, you'll probably feel a little bit

more alive the rest of the week. Um, and

this one here is retatride, uh, which is a I call it a GLP3. A GLP1 like is just an agonist of the GLP-1 receptor. This

is a triple agonist. So it binds to the GLP-1 receptor, the uh GIP receptor and that improves insulin sensitivity, so you metabolize carbs more effectively.

And then it also binds to the glucagon receptor, which increases basically energy production at rest. So you'll

burn more calories without doing anything different. And a lot of side

anything different. And a lot of side effects. Retatride has has very few. So

effects. Retatride has has very few. So

that's your that's uh that's what's on the menu this morning.

>> Do you want to just do all three?

>> All three. Okay. Yeah, why not? Let's do

all three.

>> Okay, cool. Um, so I think that a lot of people will call this pseudocience and my golden rule of pseudocience is you're not allowed to call something pseudocience until you've tried it. And

I think that before there's um clinical data and research, there's anecdote, right? The first step in that scientific

right? The first step in that scientific method is is a hypothesis typically based on some sort of empirical evidence. Um, and many of these

evidence. Um, and many of these compounds have been around for decades and there's a large body of empirical evidence that has not been effectively collated into a clinical study yet that potentially supports the use.

>> Is this more of the Brian Johnson school thought where you just start, you know, trying things on yourself and then figure out what works through the research?

>> Kind of. My fundamental problem with what Brian does is he says, I will just follow the data. And the problem with that is is that we actually cannot collect enough data points on the human

body right now to just follow the data >> right subjective how we feel also matters right intuition also matters understanding mechanism also matters you can't just look at the data because we

have a limited data set >> in the future if we have every single data point and we can model every organ then Brian's approach is correct right first principles and the limit is correct today I actually think it's a little bit flawed

>> cuz you're not getting like as much measurement especially on the actual human that's, you know, ingesting whatever.

>> Yeah. It's just like we can't measure everything. So, we need to actually to

everything. So, we need to actually to an extent also subjectively assess how we feel.

>> Um, for example, one of the things that Brian does is he tries to reduce his body temperature, which is really interesting because what that means typically is that your thyroid is under underperforming. And if you look at

underperforming. And if you look at Brian, his thyroid is underperforming.

So, what does he do? He supplements

thyroid hormone. I'm like, well, maybe if you actually step back a second and tried to actually fix the underlying problem, you wouldn't actually need to take thyroid hormone, your thyroid would actually perform effectively. Um, so

it's kind of like he [ __ ] one thing up and then he and then he tries to like fix it by by taking some sort of supplement, whereas if you actually reason from first principles, you'd probably solve things on uh the foundations.

>> Gotcha.

>> Cool. Um,

>> okay. So, what are we injecting first?

>> We're going to inject thyus now for one first. Okay. From Unity.

first. Okay. From Unity.

So, uh, a couple months ago, I I was about to fly out to the UAE for some importantish meetings, and I came down with one of the worst sore throats I had in my life. And I was about to hop on

like a 15-hour flight or something. I'm

like, "Oh, [ __ ] Here we go." Um, and I'm not good at sleeping on flights. So,

what did I do? I injected thriller one.

Um, 24 hours later, I had a really runny nose. I was excreting absolutely

nose. I was excreting absolutely everything. Um 36 hours later I was

everything. Um 36 hours later I was perfectly fine. I felt as if I never got

perfectly fine. I felt as if I never got sick. So that's thyus now for one for

sick. So that's thyus now for one for you. This is not medical advice. These

you. This is not medical advice. These

are all research compounds. Look, some

countries around the world like Russia and China and Italy um use them and you can get them easily. In the US, this is only for research purposes. So we're

performing research right now.

>> There we go.

>> How did it feel?

>> Pretty much nothing.

>> Yeah. Cool.

>> Amazing. We're going to do one more.

Pretty small needle. Let's do one.

>> Okay.

>> Let's do NAD as well.

>> Okay.

>> So, I can give you Do you want a dose that you can feel?

>> Yeah.

>> Actually, I think I've diluted this too much to give you one you can feel. But

let's let's see.

>> We'll do 50 units. So, this might >> It's crazy how little the needle actually feels like anything.

>> That burns a little bit.

>> Yeah. Cool.

>> Amazing.

>> All right. You did it.

>> Yep.

>> You're you're kind of like living a few years in the future. You've got you're taking a whole bunch of things that people aren't taking. Uh doing a whole bunch of different like injections and pills and all this stuff. What does it a week look like right now for Max?

>> Yeah. Well, I guess stepping back to the living in the future idea, when I was um 16, it was 2016. I remember wearing a big Gen One Aura ring and everyone made fun of me for tracking my sleep, right?

It was such a weird thing back then. And

then I pulled out the the red blue light blocking glasses and the mouth tape and they thought I was certifiably psychopathic at that point. And what

I've at least seen is everything I've started doing that everyone laughs at and calls crazy several years later starts to become mainstream. Same with

CGMs. Same with different headbands to track and modify human experience. Same

with some of the things I supplement today and I suspect soon. Same with

peptides and compounds that can actually enhance and extend human potential. If I

look at a day in the life um so my my general view is that there's no um universal recommendation and I think people have to be very good at

understanding what is good for them at this particular point in their life.

There was a period in my life where I woke up at 5:00 a.m. Now I wake up at 9:00 a.m. and get to bed at like 2:00

9:00 a.m. and get to bed at like 2:00 a.m. Right? And any longevity person

a.m. Right? And any longevity person that's stupid. But the reason that works

that's stupid. But the reason that works for me is that I'm very bad at going to sleep. And therefore, going to bed at

sleep. And therefore, going to bed at 2:00 a.m. means that there's a 2-hour

2:00 a.m. means that there's a 2-hour window where I'm just with my laptop and my thoughts without the world distracting me and keeping me awake. So,

I go to bed late. I wake up lateish.

When I wake up, the first thing I do is I will jump out of bed. I like literally try to jump because I find that it increases energy by 20%. Instantly. I'm

like, well, that's a pretty easy hack. I

will go to the bathroom and I will do uh a couple of things. I will use a tongue scraper because there's a lot of bacteria that accumulates in your mouth during the night. It also feels good. I

try to pay careful attention to subjectively what feels good. Yes, what

does the data say, but also subjectively what feels good for me and I will uh put coconut oil in my mouth and swish it around for around 5 minutes. And that's

called oil pooling. And there's some evidence for why this is effective from a vertic medicine. And then just subjectively for me, I have noticed that it improves oral hygiene, that it improves gum health. I remember after I

started doing it, I went to the do the the dentist and they're like, "Wow, I've never seen your teeth and gums look this healthy." Um, and then later in the in

healthy." Um, and then later in the in the dental appointment, I said to them, uh, have you heard of oil pooling? And

they're like, yeah, that doesn't work.

I'm like, hm, okay.

>> Does is it specifically for coconut oil or is it something will work for other things?

>> Um, coconut oil is is the one that is meant to be effective. I think it's antiviral and antibacterial. Um, which

is potentially why it has that property.

Um, then I'll come upstairs. I will make one or two cups of green tea. I use Goku green tea. It's a Japanese um, uh, green

green tea. It's a Japanese um, uh, green tea. I just find it's the tastiest. I

tea. I just find it's the tastiest. I

also like the caffeine response. Um I

brew that quite intentionally. U 64

degrees C water. So whatever that is in Fahrenheit, maybe 180 or something. Um

and uh that gives me around 50 milligs of caffeine, which is around right for me. I will take a multivitamin. Um

me. I will take a multivitamin. Um

there's only one brand I like of all the brands in the market, and it's not Brian Johnson's. Sorry, Brian.

Johnson's. Sorry, Brian.

>> Is there a reason for that brand that has vitamins that others don't or what's the logic? Yeah, there's probably like

the logic? Yeah, there's probably like three or four things you want to look for. One is ingredient quality. That's

for. One is ingredient quality. That's

kind of obvious, but uh for every vitamin, there are multiple forms of it, and you want the highest quality form.

The second thing is the right dosing.

Um, for example, a lot of multivitamins will have 300 IUs of vitamin D. This is

3,000 IUs of vitamin D. And I'd contend that you need closer to 3,000 IUs of vitamin D. The third thing is you want

vitamin D. The third thing is you want the right co-actors to improve the absorption of certain nutrients. So

again, take vitamin D. you need vitamin K to absorb it. Now, if you look at a lot of um vitamin K's that are added, they might add one form of vitamin K.

There's actually three forms you need.

You know, you you need vitamin K1, you need K2, and of K2, you need both the MK7 form and the MK4 form. And no

multivitamin is thinking about all of this stuff except for this one brand.

And then the final thing that uh I look for is just having a broad enough spectrum of the things that I want in my body. So, I'll take that. I take um

body. So, I'll take that. I take um fatty 15, which is kind of like an alternative to omega-3. I'll take that in the morning and then omega-3 at night. Um and then I'll take torine um

night. Um and then I'll take torine um which is good for longevity, energy, and several other functions. And depending

on what I'm going for on a certain day, I might supplement other things. If I'm

trying to improve verbal fluency, like I want to do now for a podcast, I will take L otine, which for some reason for me improves uh verbal fluency. It doesn't

for everyone. Um, if I'm trying to lock in and focus and get into deep work, I'll likely take nicotine or some sort of colonergic like alpha GPC. So,

depending on exactly what I'm going for, I'll take different things. I get to work, I don't eat until, nowadays 4 p.m.

This has changed. I've been parts of my life where I eat first thing. Now, I

don't eat until 4 p.m. I make a massive smoothie. This smoothie is a hack. has

smoothie. This smoothie is a hack. has

60 gram of protein, 30 grams of fiber, um dozens of nutrients, dozens of things that support gut health, and only maybe 400 calories, but it fills me up more like 1,000 calories.

>> Do you take that every morning? And like

do you have a very specific set of things that you put in it?

>> Yeah, I would do that every uh afternoon now at around 3:00 to 4:00 p.m. And I

will had add three different forms of protein. Um I I will add a organic goat

protein. Um I I will add a organic goat whey protein which is high in amino acids like leucine um which is good for muscle building. I'll also add a plant

muscle building. I'll also add a plant protein because the amino acids in the plant protein are different to the one in the whey. And then I'll also add a collagen because that's high in glycine and things which are low in whey. And I

find that if you want to balance amino acid profile it's helpful to add multiple different forms. Um I'll add different kinds of fiber. So, I'll add cream banana flour, which is one of the few resistant starches you can get, and

resistant starch is really good for your gut. I'll also add a soluble fiber.

gut. I'll also add a soluble fiber.

There's all sorts of different ones, soluble fibers you can use. Um, I'll add colostrum. I'll add um glutamine. I'll

colostrum. I'll add um glutamine. I'll

add a high polyphenol cacao powder and a handful of other things that get a lot of nutrients in a way that fuels you up, is very high in fiber, very high in protein, very easy to do. And I find

that kind of a hack. Um, I'll do that.

I'll go to the gym. I'll exercise. I'll

come back. I'll eat a really big dinner.

And then I will lock in and work work for the rest of the night and do a sleep stack before bed. And

>> wait, what's your sleep stack?

>> Um, so there's two. There's one which is like frequent, regular, very safe, and that's basically just amino acids and that will be atheanine. Um, it will be

glycine. Um it's around 200 milligrams

glycine. Um it's around 200 milligrams of althanine, around three grams of glycine, 100 milligrams of anositol, and

uh around 600 milligs of magnesium. Um

and that's the simple stack. That's one

that I'll do most nights. If I want to induce sleep onset um because I'm feeling like I don't I'm not going to be able to sleep, I'll add a couple of other things. I might double the dose of

other things. I might double the dose of theine. I might add 250 millig of

theine. I might add 250 millig of pharmarmacaba. And I might add around a

pharmarmacaba. And I might add around a milligram of melatonin. Um, so that's and maybe I'll add a gram of elptophan as well, which is another amino acid.

>> And like a milligram is like 1if of what they typically sell in like a tablet, right? Cuz they typically sell like 5

right? Cuz they typically sell like 5 milligram tablets, I think.

>> And like in the US, people have gone overboard with melatonin. And I don't think that you actually have a high marginal benefit. And I think the higher

marginal benefit. And I think the higher dosing of the higher dosing of melatonin can actually impact your body's natural ability to produce melatonin. The other

thing I've noticed is like when I take a higher dose of melatonin, I just wake up halfway through the night, I just can't go back to sleep. Okay.

>> Um, which I but it's like consistent.

So, I know that there's like a direct correlation with that.

>> Um, >> well, I think I think there's an interesting meta in there, right, which is there's the general objective truth, which is does melatonin wake you up in the middle of the night? And then

there's like the the for me what happens. I think the for me what happens

happens. I think the for me what happens is really really interesting. And in

today's world, we're not good at performing individualized randomized control trial or individualized trials controlling against our own body. I

think where we need to get to with health is we use our own body as a control and we learn what individually works for us. And it's going to be very hard for the human brain to do that because a doctor can't do that for every

single individual on Earth. The AI will probably get to the point where it knows exactly what works for us because we've built a closed loop feedback system of intervention and result uh uh

therapeutic and diagnostic and the AI will tell us here's exactly what you need to do and in this world we will I think blindly follow the AI because we know it is far better than what we can work out on our own

>> or like at least the people that want to be super optimized for their health. I'd

imagine >> uh I don't know. I think like that's kind of where it starts and I think in a world where the AI is imperfect, that's where it starts. But the idea is if the AI actually has full context on what you

care about, it will know whether you are maybe not caring about being optimized for your health and it will give you the recommendation based on that. So I think if we assume that context is genuinely infinite, one of my hypotheses is that

we actually blindly follow the AI for most for most decisions in our lives.

>> Yeah. I think I think that like the less cognitive load you have, the better. And

people really don't like to think >> honestly and make decisions.

>> Yeah. And and like people say, "No, but I want to make decisions. I want to choose the restaurant." The AI is never going to know my preference. I'm like,

"This assumes that you don't have infinite context." If the AI has

infinite context." If the AI has infinite context, I don't think people are going to want to make these decisions.

>> Do you think that like there's some future iteration of or version of superpower where I'd imagine to understand how your body is reacting, you have to have some uh thing that's

kind of taking in signal. And so do you have like a wearable or how do you get that information?

>> Yes. So there's three kinds of data which are helpful in healthcare. No

single company has all three of them. If

we can gather all three of them, we potentially build the AI doctor that redefineses medicine. We build the

redefineses medicine. We build the system I'm talking about. The three

kinds of data are one multimodal multiomic data. So think your genome,

multiomic data. So think your genome, blood, biomarker testing, proteomic testing, metabolomic testing, biological assays. the and you and you want

assays. the and you and you want multiple kinds of them over time. The

second kind of data set you want is longitudinal clinical data which is basically what happens to someone over time. Do they do they become healthier?

time. Do they do they become healthier?

Do they become less healthy? That's

basically the label on the omic data.

And again, it's very rare to have both these data sets in concert. If you look at 23 and me, yes, they have genomic data, but they don't have clinical data.

They don't take care of you over time to see what happens. They give you a big survey when you join and that survey plus the genomic data is worth uh $300 million for someone trying to like

acquire acquire 23 and me. But they

don't see what happens over time. The

second thing you need is longitudinal clinical data. The third thing you need

clinical data. The third thing you need is continuous wearable data. And the

reason why is because today what we try to do is we try to map from omic data to clinical data. We try to say I saw this

clinical data. We try to say I saw this in your genome and therefore I predicted this outcome and that is very episodic.

You can't do blood tests that often and therefore prediction is not that effective. What we want to potentially

effective. What we want to potentially do is move to continuous prediction. I

saw this thing in your wearable or in some sort of bio sensor in your environment and that allowed me to predict what is happening clinically. So

having all three of these data sets in concert right now is something we do and if we build up enough data there we start to be able to create the AI doctor.

>> Yeah. Does that include stuff more than just, you know, your personal wearable, but it's also like the I don't know, if there's smoke in the air or something outside, you might predict that your body is reacting less well or something.

>> Yeah, we want to lower the barrier to collecting as much data as possible. And

what we might see is that the iPhone can scan your face, and that is a useful data point. The iPhone can see how fast

data point. The iPhone can see how fast you're typing, and that's a useful data point. um there's some sensor in your

point. um there's some sensor in your environment that collects uh it collects data about your environment and that's a useful data point. So yeah, as much we want to lower the barrier of collecting

continuous data because of how that will be useful for for prediction.

>> Is this is this a company that just couldn't get built like six or seven years ago? Is this something that it can

years ago? Is this something that it can only get built now?

>> Uh yeah, I think the the company that tried to do something similar to what we're doing was Forward. Um they burned $400 million and got nowhere. And

there's a few reasons for that, but I think one is that there were very few APIs and and and very not much healthcare infrastructure. And that mean

healthcare infrastructure. And that mean they that meant they had to try to build every single thing themselves. And they

end up having like five to 10 companies in one. Um and at the same time, APIs

in one. Um and at the same time, APIs got built that basically said, let's take one part of the health stack and turn that into infra. And now a company like Superpower can come along and do a large chunk of what Ford does in a year

with $10 million rather than $400 million because there's there's healthcare infrastructure. Interesting.

healthcare infrastructure. Interesting.

>> And and then there's there's a couple of other trends, right, which is that the cost of biological assays are going down. The prevalence of wearables are

down. The prevalence of wearables are going up. Language models are quite an

going up. Language models are quite an effective modality at connecting the dots across lots of data points. Um more

people actually care about health. So

more people are opting in, deciding to pay us to perform this kind of testing.

So there's technological trends, there's uh biotechnology trends, and then there's also consumer trends.

>> Do you kind of think I know you mentioned nicotine um is that kind of been scapegoed the past few years? You

know, when people think of nicotine in most cases, they think of like cigarettes equals bad for you because there's, you know, cancer stuff or carcinogens and stuff. Um what form of nicotine do you think is a good form of

nicotine? Like a powder or pouch?

nicotine? Like a powder or pouch?

>> Yeah. So I think that it depends what what your goals are. My gen one of my general views is that IQ is one of the most important inputs into being able to create great things in the world. If we

believe this, what we're trying to solve for is how can I increase my IQ, increase my focus, increase my ability to come up with interesting ideas.

If we fix that goal, we say, okay, well, nicotine is one of the things that allows us to do that very effectively.

It's a really potent neutropic. It is

very safe. The risk of developing any sort of disease using low amounts of nicotine infrequently is very low. Some

people say nicotine has all sorts of protective properties. Some say it's

protective properties. Some say it's neuroprotective and it might reduce incidence of Alzheimer's. It's a very wellstudied and well understood compound. For anyone who is questioning

compound. For anyone who is questioning nicotine, I would recommend them to go to Gwen.net, gw.net, I think nicotine or there might be a something. So just have a look at the

something. So just have a look at the nicotine article on that site and it aggregates so much of the research about nicotine and says it's actually quite safe. So I was staunchly anti-nicotine

safe. So I was staunchly anti-nicotine because I hadn't actually looked into the research and I hadn't thought for myself. Instead I listened to everyone

myself. Instead I listened to everyone else and now I'm quite pro nicotine.

>> Yeah. I I I was basically completely anti-nicotine or not necessarily anti-nicotine but definitely not going to you know pick up smoking and stuff.

Um, but then I went down to Elskundo and everyone was either smoking or using you know a ridiculous number of uh like Lucy pouches because you know John Kugan sponsored them and it was just very

obvious like after using them for a few times I was like this is useful but like super low dose like three milligrams and stuff.

>> Yeah.

>> Yeah.

>> I think it depends what for. I think

nicotine is part of like a pro- autism stack and then sometimes you want the anti- autism stack. So pro pro- autism stack I think is nicotine plus some sort ofergic. to increase acetylcholine

ofergic. to increase acetylcholine secretion in the brain. Alpha GPC is an example. Phosphetylcholine is an

example. Phosphetylcholine is an example. CDP choline is another example.

example. CDP choline is another example.

I think the anti- autism stack are things that increase uh GABA or serotonin.

>> Would this be like a a you know a psychedelic kind of thing?

>> So psychedelics would be probably anti- autism. U MDMA is anti- autism. Um

autism. U MDMA is anti- autism. Um

pharmagaba is anti- autism. Theine is

anti- autism. Fenobut is anti- autism. I

think alcohol is anti- autism. alcohol.

Actually, red wine increases GABA. And

>> do you want do you want to talk about your thoughts on red wine quick?

>> Um, look, I think it's been overly demonized. Um, there's a couple of ways

demonized. Um, there's a couple of ways to think about this. One is let's just be strong empiricists and let's look at all the empirical and epidemiological evidence we have and say, is there any

observed correlation between low amounts of alcohol consumption and lifespan? And

the answer is no. If you look at blue zones, just about all of them will consume small amounts of alcohol. The

second thing is we can be okay let's just reason by first principles. Let's

try to look at mechanisms. And if you try to look at mechanisms there are very few mechanisms that can uh create that that can allow you to to create an argument for saying one glass or half

glass of red wine a night is bad for you. And for every argument that says

you. And for every argument that says it's bad for you, you can also argue the opposite. You could say it's an

opposite. You could say it's an antioxidant. You can say that it reduces

antioxidant. You can say that it reduces stress. You can say it's done socially.

stress. You can say it's done socially.

You can say it's antiviral and antibacterial. Then the final thing is I

antibacterial. Then the final thing is I can be like okay let me just look at the people who um have have like who who are at the frontier right who who are the people at the frontier who have been

delivering care for a long time and what do they say one of our uh doctors is probably the leading cancer doctor around the world people fly from all around the world to see her and she

cures incurable cancers incurable autoimmune diseases etc. If I look at what experts such as her say, um she'll she will personally drink half a shot of tequila every night because she enjoys

it, right? So I think it's very hard to

it, right? So I think it's very hard to create an argument that um between one to call it five glasses of a healthy form of alcohol per week is is bad for you.

>> So what is your regimen? Do you drink like that?

>> Um >> what is your stack?

>> I focus a lot on what brings me joy.

Mhm.

>> Like I I think a lot about one of the biggest inputs into health and lifespan is am I happy? Am I enjoying myself? Am

I relaxed? Am I not overintellectualizing absolutely everything? And if I'm out at a

everything? And if I'm out at a restaurant and there's a nice glass of red wine, I will have a glass of red wine. Now, will I have five glasses? No.

wine. Now, will I have five glasses? No.

Will I do that every night? No. But if I get joy and satisfaction from drinking a very small amount, I I happily will.

part part of it is spacing it out over the week so you aren't slamming all five glasses at once.

>> Yeah.

>> Or just do it for an entire month, 20 in one night.

>> Now, that said, um I'm increasingly thinking there could even be an argument for doing a large amount of alcohol all at once.

>> Okay, >> and um from a increasing the odds of success

standpoint, right? So um my my uh

standpoint, right? So um my my uh general view is the two variables that matter the most for success are IQ and

um low fear. And I think having one night a month where you get quite drunk in an intentional way can solve for both these things. I think it can solve for

these things. I think it can solve for IQ because it changes the way you think over an acute 1-day period. And one part of IQ is creativity or lateral thinking.

But I think more importantly, it solves for low fear. It basically shows you what does having no inhibitions feel like in my body. And if you can take that set of feelings and learn how to bring that up even when you're not

drunk, you now all of a sudden have a superpower, which is that you can take more action with less fear even when you're not drinking. So again, I don't get massively drunk once a month, but

I'm increasingly thinking there could be an argument for why it's actually a highly productive thing. Do do you think that you would do this uh once a month or once you know a year or what's the

like optimal uh I don't know time frame in which you remind yourself?

>> I probably think once a month >> is probably optimal and it's hard to argue that doing it once a month is going to have an adverse effect in your health as well. Is there any other thing kind of like getting slammed once a

month that um that people in most cases might, you know, doctors or whatever might be like, I don't know if that is the right thing to do, but based on your, you know, experience, it seems like the right move.

>> Well, depends what we say it's the right move for. Is it the right move for

move for. Is it the right move for maximizing my health today? Probably

not. Is it the right move for helping you build something great? Potentially.

Like if we genuinely believe that it has a positive effect on IQ by changing the way you think over a short-term period and a positive effect on lowering fear, it might be an input into building

something great. And at the same time, I

something great. And at the same time, I think all these micro optimizations are not going to materially move the needle on health span or lifespan. They're not.

The thing that is is deep biotech. And

we can assume that access to deep biotech is unevenly distributed. So the

thing that moves the needle in health is having the money, having money to afford deep biotech. And if improv increasing

deep biotech. And if improv increasing IQ and lowering fee allows you to make more money, then actually drinking alcohol might increase lifespan.

>> It's like the game optimal move.

>> Maybe like look, I could argue against myself right now. I think I'm like being rhetorical for the sake of it. But but I I think that the meta here is that people are overoptimizing on things

which have very low marginal impact. And

the reality is the way we extend lifespan is deep biotechnology, not did I have zero glasses of wine over the past 3 years. What do you think the biggest thing that most people could do that they're just not tracking or not

getting enough of uh to like materially improve their general health?

>> I think that one is just testing and seeing what is wrong with you. Um when

you test and you see what's wrong, you can start to fix those things with very simple interventions and you also start being motivated to fix those things. I

think the second thing is uh I was a short story. So this cancer doctor I

short story. So this cancer doctor I mentioned, one of the best cancer doctors in the world, uh I asked her, "What is the number one thing you recommend to prevent cancer?" And she

replied, "PMA, positive mental attitude is the number one thing you can do to prevent cancer." And I think there's a

prevent cancer." And I think there's a really interesting learning in here, which is that the the the way the the the way we like appraise our

everyday life, the way we choose to feel actually has a really big impact on biology, right? We know that the

biology, right? We know that the subjective can modify the objective.

What exists in our brain can actually modify our biology and the world. And I

think not enough people in the world of health actually give weight to the impact of psychology and the brain and the subjective on modifying our actual reality. Um so PMA is something which I

reality. Um so PMA is something which I think is massively underpracticed.

>> Is it is it kind of like uh when you're happy you just release different kinds of chemicals in your brain and your body or what what is it? Yeah, there's

there's a lot of uh uh anecdote and some research to say that what we believe uh actually creates or or or becomes reality. And we can do that at the very

reality. And we can do that at the very micro level of if I believe this about a drink, it will have this effect on my biology. And there's all sorts of

biology. And there's all sorts of interesting studies. Um and I think the

interesting studies. Um and I think the way to put this into practice is to every day say I'm healthy and I'm happy.

Like I think my problem with the aura ring is people now have 7 hours of sleep and they wake up and they're like [ __ ] my sleep score 70. I'm going to choose to feel [ __ ] today. Um whereas I think

the opposite approach is I wake up and I feel amazing so I'm going to choose to feel really good and I'm going to choose to be really happy. And we know there we know the studies between happiness and longevity and happiness and lifespan or

low stress and lifespan. And I think it's a often people assume that the environment determines our happiness levels and our stress levels. I would

contend that we can actually modify our happiness and stress levels by just choosing to do that, right? It's

actually a very malleable thing. Which

is why I dislike the question, how are you? Because it assumes that how you are

you? Because it assumes that how you are as a product of the world, whereas I think there's only one valid answer to how are you, which is really [ __ ] good. I'm like choosing to be really

good. I'm like choosing to be really [ __ ] good right now. Um, so that that that's kind of how I think of PMA.

>> Amazing. I I think that there's like very few people like you to be honest.

I think I think most people are a little bit more uh influenced by their environments, but you're also you're you're kind of like manufacturing an environment where you can be this like version of yourself that is happy,

>> you know, like you can't, you know, >> if you're living out of your car, for example, it's a little bit difficult, >> but not everything around me has to be really [ __ ] good, right? Stuff can

around me can be really hard. I can be going through a low and at the same time, I can choose to be like, good, like, yeah, I'm going through a low.

Good. this is an awesome opportunity to actually develop myself and improve. So

I'm not saying that everything around you has to be good. I'm not saying that um everything that happens to you has to be something which is like a good or bad event. The events can be bad but I can

event. The events can be bad but I can say that a bad event for me has a good component to it. I can appraise that event as doing something positive. I can

appraise a tough event is doing and it doesn't mean I'm not going to feel hurt.

It doesn't mean I'm not going to feel sad. It doesn't mean I'm not going to

sad. It doesn't mean I'm not going to feel really angry but like good. I'm

feeling those things. That's fine.

That's human. That can actually be a good thing.

>> Yeah. The way the way I think about it is I just pretend that I'm on a quest and it'd be very boring if the quest like everything worked out and it was just this, you know, clear step lighter up. You know, if you uh don't get enough

up. You know, if you uh don't get enough sleep one night, you're just on a quest, right?

>> I feel like you have this mentality of bit as well, like you have this crazy resilience positivity.

>> Yeah. No, I Well, I just like I I I love this line, just figure out what works and then do it. Like I think that's from Charlie Mer and it's like if you know people like happy people, people like people that they enjoy being around and

we are very like influenced by the people around us and so >> if you smile it like causes chemicals to be released in your brain, you know, if I do it. So uh anyway, okay,

>> just on the on the Charlie point, I love people who have two supposed who hold two supposedly paradoxical views um at the same time. So Charlie has two views.

One, the algorithm of life is repeat what works. Two is don't copy others.

what works. Two is don't copy others.

Don't follow the herd. Um, reason from first principles. Be a fundament like

first principles. Be a fundament like reason from the fundamentals. Question

everything. And he holds both of those views at the same time. And I actually kind of love that because I think you can hold both of those views at the same time.

>> Yeah. I think I think one leads into the other. First you question the thing that

other. First you question the thing that you know is the conceived or conventional wisdom and then if it is actually right then you just do it forever because you don't need to relearn. Do you have any views in your

relearn. Do you have any views in your own head that kind of are mutually conflicting a little bit?

>> Uh yeah, many. One is that I'm simultaneously someone who likes to reason from fundamentals and I say that I'm a strong empiricist.

>> So the strong empirical view of the world says I do not understand the fundamentals. I'm just going to look at

fundamentals. I'm just going to look at what empirically is true and assume that is true even if I don't understand why.

All right? So, a classic example, I have a lot of friends who ask me, um, should I start my company in Australia or the US? And they will say, here are all of

US? And they will say, here are all of my reasons for starting the company in Australia. And if we just reason from

Australia. And if we just reason from fundamentals there, from first principles, often I'll be like, yeah, those reasons sound really good. I think

you're right. You should start your company in Australia. If I'm a strong empiricist, I say, I don't give a [ __ ] about your reasons. All I care about is what does the empirical data support?

I'm going to assume I don't understand all of the reasons. And the empirical data supports the fact that if you want to start a great company, you should be in the Bay Area with a deep tech exception of in LA and maybe like a CPG

and fintech exception in New York. So

the strong empirical view is moved to the US. Now at the same time, I believe

the US. Now at the same time, I believe that often a lot of the dogma is wrong, right? Often we shouldn't reason from

right? Often we shouldn't reason from analogy and shouldn't reason from dogma and shouldn't follow advice and instead should say what is fundamentally true.

Right? how I'll have a lot of people be like, "Oh, this company did this thing with their product team. Let's do that."

I'm like, "But why?" Right? Like like

why? That doesn't work for our specific situation. In our specific situation,

situation. In our specific situation, here's the set of facts, and this is the conclusion based on that set of facts.

So, I think there are two conflicting views that I simultaneously hold. There

are a bunch of others, but I I'll start with that. I

with that. I >> I think you talked about like uh MASA a lot. Um, can you tell me what makes or

lot. Um, can you tell me what makes or what you find special about Masa and like why you have studied him?

>> He is one of the only people who dreams big enough. I was watching an interview

big enough. I was watching an interview uh with Masa in January and the interviewer opens with Masa. Here are

all of the things you've done. It's

amazing. You raised hundred billion dollars, blah blah blah. And master

says, "I fear that in my 65 or however many years of life I've spent on this earth, I fear that I've wasted every year and I've done nothing yet and I

haven't dreamed big enough yet." And

that is [ __ ] awesome, right? The

world makes it so hard to dream big.

It's so scary for people to be ambitious enough because people laugh. When Master

said, "I'm going to raise $100 billion," everyone laughed. People today still

everyone laughed. People today still call Master an idiot. He takes so much risk. He's stupid. He doesn't know what

risk. He's stupid. He doesn't know what he's doing. He just like flies by the

he's doing. He just like flies by the seat of his pants. No one gets it.

>> What's What's funny also is like it it it actually works. Like if you look at even the whole like hundred billion dollar raise or whatever on the plane ride over to Saudi Arabia, he like decides what number he's going to ask

for and I think it was initially like 15 billion and then he was like no 100.

Just wrote it down and then asked for it and he got 45.

>> Totally.

>> So you don't get what you don't ask for kind of thing. like like lit literally I I believe in the meeting with one of the people who anchored the fund >> he was planning to ask for I think it was $10 billion >> $10 billion >> and he was 45 minutes into the meeting

and they said how much are you looking to raise like $45 billion >> like 4x the number and this isn't this isn't 100k to 450k right this is 35

billion delta we're talking about because you know he wanted to raise a billion dollars per minute so so that's Masa and I think he has a very good

understanding of how the biggest ideas and the biggest trends can be far bigger than anyone else actually ever thinks, right? It's the whole like Thrive idea

right? It's the whole like Thrive idea of buy Fifth Avenue. And I think that consensus and right is actually a very non-conensus idea, right? Because

consensus and right typically means betting far bigger and believing that the best of the best can compound far faster than anyone else believes. And

that belief is actually non-conensus.

And Masa holds that belief. Let's take

let's take the ambition angle, you know, from Masa. What about like how you think

from Masa. What about like how you think and how you approach things is different because you're trying to constantly think about what is the more ambitious version of what I'm trying to do.

>> I think there's three frames that people should think about in the context of building a company um or three guiding questions. Question number one is um

questions. Question number one is um assume you have to be a hundred billion company in around 10 years. Maybe it'll

take 15, 20 years, but I assume you have to do it in around 10 years. What has to happen? What has to be true? How can you

happen? What has to be true? How can you get there? And that's an amazing guiding

get there? And that's an amazing guiding question because it means right from the start, just about every single idea you could work on is not worth working on.

>> Yeah.

>> Like no SAS idea is worth working on anymore.

>> It just makes it easy to say no.

>> It just makes it easy to say no, right?

You need to work on something that actually matters for the world and can progress humanity forward because that allows you to create a hundred billion dollar company in around 10 years.

The second view is how do you be a billiond dollar company in 3 years? So

few people try to think this way. But

the second you fix the assumption that we need to be a billion dollar company in 3 years, you start to make a different set of actions. You hire

different people. You raise money in a different way. And I'm not saying you

different way. And I'm not saying you will be a billion dollar company in 3 years, but what if you operate under the assumption that you have to be? I think

that is really, really powerful and only happens if you dream big. The dogma of the world will tell you that's stupid.

if you say this on camera, people will laugh at you. Like be less ambitious.

Come on, no one does this. So I think that's the second um frame. And then I think the third frame is how do you get to and this isn't useful for every company, but it's how do you get to 10 million in revenue in one year and the

only reason this is a useful frame is that um revenue is typically the primary input into capital which is the primary input into team which is the primary input into product. Right? So if we actually use that line of reasoning,

it's like actually let's get a lot of capital early and revenue is one thing that unlocks that. If you're palmer lucky, that's not that's not the case.

If you're if if you're Elon, that's not the case. If you're a first-time founder

the case. If you're a first-time founder who's moving to the US at 22 years old, that might be the case.

>> Yeah. That's one of your main constraints. Yeah. Okay. So you have

constraints. Yeah. Okay. So you have this like long-term vision. You think,

you know, putting like setting really auditious targets and then also like working backwards on how do you get there? How do you think through you know

there? How do you think through you know find figuring out what the critical path is at any given moment and then just like relentlessly executing on that to make the end goal of a year or 10 years work?

>> I think a couple of things have to um be true at the same time. So I think one is you need to know more or less the end state and the next best step but you don't have to know most of the things in

the middle. So for the most part I think

the middle. So for the most part I think a lot about uh how can we be a billion dollar company in 3 years how can we be a hundred billion company and then today what is the fastest path to like 20 mil

revenue or 50 mil revenue and they require very different kinds of thinking the hundred billion kind of thinking requires you to be very opinionated to have views that others don't have to

make certain assumptions about how the market evolves whereas the 10 million in one year or the 50 million in a couple years view says the exact opposite. It

says, "I'm going to have very few opinions. I'm actually going to be very

opinions. I'm actually going to be very consensus. I'm just going to focus on

consensus. I'm just going to focus on what does the market want? Where is the market at today? What works?" The

Charlie Mer idea. Let's actually assume that my opinions, even if they're correct in the limit, may not be true today, right? So, let's actually focus

today, right? So, let's actually focus on what is true today. So, those two things simultaneously have have to exist. Um, and then there's the question

exist. Um, and then there's the question about how does that action I'm taking today actually potentially put me on the critical path there? And the way to work that out is not by sitting there and twiddling your thumbs and thinking about

things. It's actually just taking

things. It's actually just taking action. I do think action creates

action. I do think action creates information. So know the thing you have

information. So know the thing you have to do today. Start taking action. Assume

you're smart enough to continue to change and modify the kind of actions you take based on the information you get to put you on the critical path to building the the thing that's great. Do

you have a few examples of paths that you thought at some point in time were the optimal path and then you figured out at some point, oh [ __ ] this is the wrong direction to be going in? You

know, after new information came, >> there was a period of time where I had a similar hypothesis to Ford, which is that you needed to own actual clinics.

And the belief there was that a lot of things in health actually require the physical environment and the physical world and therefore you need some physical place to interact and interface

with the person. I no longer believe um that is the case. Um there was >> How did you how did you make that transition? Like what led you to believe

transition? Like what led you to believe that that wasn't the right model?

>> I just think that most things that you would do physically can be done um at home and if you need to physically interface with someone, you can do that without the capex constraint of a clinic. I also think if you fix the

clinic. I also think if you fix the assumption that you need to be a billion dollar company in 3 years, you basically say, well, we can't do something physically because it doesn't have this in the limit. Maybe you can open the

Apple store or you can have some sort of location that allows you to therapeutically interface with with a human, but like that's something that can evolve over time. Um,

so that that's like one one example. Um,

I think the another example is what one of our guiding principles in the early days was let's take high-end concurge medicine that costs $100,000 a year or $500,000 a year and make that

cost as close to zero as possible, right? And our belief is that is at

right? And our belief is that is at least today the the the the local optima of of healthcare. It won't be in the best today. So, let's try to democratize

best today. So, let's try to democratize access to that. And our hypothesis was to do that let's start by offering a 5k membership and then we'll move to 2k and

then 1k etc etc. The problem is the second you anchor to a 5k membership you you operate as if you have 5k to play with obviously you start including humans in the loop you add more services

you don't build as much technology and you create you do not create the forcing function to actually reduce price. So we

started at between 2 to 10k and that was a mistake. What we then did is we said

a mistake. What we then did is we said you know what let's fix the price at $4.99 and let's operate with the constraint that the price is $499 a year. And all of a sudden it's like well

year. And all of a sudden it's like well goodbye humans there's no there's no like we can't do anything synchronous with humans. Great. Let's let's not have

with humans. Great. Let's let's not have humans in the loop and let's triple the size of the engineering team. Are you

trying to like actively stop yourself from kind of like getting on the IV drip of a local maxima when you know that the global like thing is basically you have to serve kind of everyone and you're trying to design a product that could do

that >> 100%. The temptation of the 10k

>> 100%. The temptation of the 10k membership >> is that we can have a thousand members and do 10 million in revenue.

>> It's like whoa that's not that hard. I

think we can do that pretty easily.

>> You could probably do that in a year probably.

>> Yeah. Three people a day.

>> That's that's not that hard. So in the short term, if all we did was optimize for revenue in the short term, we would price higher. And a lot of people as a

price higher. And a lot of people as a result will say, "Pric higher. Look at

the revenue." But what they don't realize is that they're just looking at the short-term payoff curve. The game

we're playing is the long-term payoff curve. And we will happily go into a

curve. And we will happily go into a slightly deeper J curve where we need to spend more money on products, supply chain, operations, technology because we believe if we do that we start to create

a membership most people should own which has a far greater local optima potential potentially are being the global optimum. Are you trying to take

global optimum. Are you trying to take the same model as kind of like an early Amazon Prime where you're basically understanding that you're going to get the whales at the beginning or not necessarily in this case, but you're not

going to earn as much money shortterm, but long-term once it scales to everyone, you're making way more money.

>> Yeah. So, I guess like an interesting thought experiment here. So, there's

three parts to what we do. Two of them are the membership. You'll have 100 plus blood diarkers tested. That will cost $2,000 in the hospital. All your data in one place. past medical records,

one place. past medical records, wearables, access to the AI that tells you what to do, access to a 24/7 medical team, primary care, urgent care, prescriptions referrals care navigation, um access to a protocol that

tells you here's exactly what you should do, and then an ecosystem with 20% off all supplements, pharmaceuticals, and diagnostics, castle, right? That product

most people should genuinely own, right?

The test itself is going to cost 2,000.

>> You want to basically make it like stupid for you not to own.

>> Totally. The 20s of supplements and pharmaceuticals will pay off super quickly. And we have the second part of

quickly. And we have the second part of what we're doing is the ecosystem. So

we've said in the short term let's be a horizontal wrapper on top of all supplements, all diagnostics and all therapeutics. Let's bring everything

therapeutics. Let's bring everything into one place and make it 20% cheaper and only have the best. So as a thought experiment, let's assume everyone let's assume only 10% of people own this,

right? 10% of people own the membership

right? 10% of people own the membership and let's assume they spend only 10% of the dollars with us. Why wouldn't it's 20% off everything. That's a $200 billion company. 10% of 10% is a $200

billion company. 10% of 10% is a $200 billion company, right? Um, and all of a sudden we're like, whoa, okay, this is a far greater local Optima than the 10K a year membership that might cap out

pretty quickly.

>> Interesting. Okay. Um, and I know you mentioned in another thing, uh, that you're basically talking about or you're thinking about brand and you believe that most companies have like a two or

three out of 10 brand um, and that you're at like a six or whatever. How do

you think about like what makes a great brand and how do you get that last like three or four points?

>> Yeah. So, first the philosophy here which is that um everything sits in a convex curve meaning 9 out of 10 is 10 times better than 8 out of 10 which is 10 times better than 7 out of 10.

>> The second philosophical point here is that just about every single thing in the world is around 4 out of 10.

>> There's two implica there's a couple of implications from this. One is you cannot copy what is out there because the best of what is out there is four out of 10. The second implication is if you create the new best of what is out

there, it's still probably only six out of 10. And that's a really empowering

of 10. And that's a really empowering belief because it means you can keep being better. You can keep being better.

being better. You can keep being better.

You can keep being better. The third

implication of this is that uh to actually get 6 out of 10 or 7 out of 10, it takes a lot of work, a lot of effort, a lot of focus. And because it's so so hard that because the returns are

exponentially distributed to getting there, you should really focus on getting there. And therefore, you should

getting there. And therefore, you should do fewer things, you should be very focused, you should really just try to get to great. So there are a few of the underlying philosophical beliefs and I capture these beliefs with the term

convexity, right? This most things

convexity, right? This most things follow a convex distribution. Some

people call it a power curve, whatever.

Um, in terms of actually building a great brand, I think brand at the core is a set of beliefs, right? So before

you think about what's your company name or what color do you use, it's like what do you fundamentally believe and what do you believe that others might might not believe. Right? If you look at religion,

believe. Right? If you look at religion, religion at a core core is a set of beliefs and everything else builds on top of those belief building blocks. So

that's where we started. We started with a manifesto before we had anything else.

We started with a set of beliefs about the future, about health, about humanity. From there, all we're trying

humanity. From there, all we're trying to do is express those beliefs using colors, using a visual identity, using a website, using language, using copyrightiting, they're all just

expression of the fundamental beliefs.

And my view is that people chronically underinvest into brand, right? If we

genuinely believe that brands are exponentially distributed, pe the implication is people are underinvesting. The other thing too is I

underinvesting. The other thing too is I know that like people spend a huge amount of money on like sales and marketing but that's not necessarily brand like that's not the image in people's minds like I think I think that when you think of like Apple or at least

Apple from you know 20 years ago or whatever you're thinking about this this thing this this brand or or mission that you are personally aligned with whereas most like sales and marketing is just

like buy the product you know it's not the why you're not buying the why behind the product.

>> Yep. 100%. I think strong brand foundations support sales and marketing.

>> Yeah. right? You still need sales and marketing, but I think when it sits on top of a stronger brand foundation, you can compound for longer. Um, and all of that again is just sales and marketing is really just a reflection of a core set of beliefs.

>> You mentioned that it's basically just one person working on the entire superpower brand. Um, how'd you how'd

superpower brand. Um, how'd you how'd you find her?

>> Um, so we have more people now.

>> Um, but but Hannah um did a lot of all of everything we did in the early days.

>> Yeah. And uh one of my beliefs is that talent is exponentially distributed >> or talent follows a convex curve.

Meaning that there are only maybe a couple hundred or a couple thousand people in the world who are actually good. And you should just obsess about

good. And you should just obsess about finding those people and working along those people um alongside those people.

and and Hannah on our team, don't hire her, everyone listening, um is you won't be able to hire her is so so like she quit a job at Canva when she was 17. She

was the youngest person at Canva. We

co-founded a company together previously. Um and then Hannah was 19

previously. Um and then Hannah was 19 years old running a solo design agency doing a million dollar a year, like $500,000 a year. And we're like, Hannah, I know you're making a lot of money, but

you want to did you want to work on something more important? and and um Hannah Hannah joined the team really early on.

>> Well, how much time so when you when you find one of these people I because there's so few of them, you know, logically it would make sense to spend a insane amount of time and an effort and

energy trying to get that person on board once you know that they are really that special. Um do you have any uh what

that special. Um do you have any uh what have you done that's outside the normal bounds of what people normally do to hire someone to find those people in the past?

So, one of the things I think I have a high believability weight on is identifying talent quite quickly because it's something I really obsess over. Um, and

what that means is that within 10 minutes of chatting with someone, I typically know whether we want to hire them. So, once I've more or less made

them. So, once I've more or less made that decision, every subsequent interview, there might be 10 of them, there might be 20 of them, but every subsequent interview is actually a sales

um sales process. So I I I I will after chatting with someone in the first call try to deeply understand what do they want like what what what what do they want in life what are their goals what

makes them happy and then I'll try to construct an interview process that shows them how we can genuinely give them what they want it has to be genuine right smart people they they'll see whether you can give them partially like

maybe reconfiguring how you do things to fit what they need >> 100% and I'll say okay so then we're going to set up these three interviews or these three chats and I'll say this

interview is 70% sales 30% interview right or I'll say this is 90% sales 10% interview um and uh a candidate will go through a process of interviewing which

is actually being sold on the company if we think they're good enough and my view is that if uh we can make superpower the best the fundamentally best option for them they should join if superpower is

not the selfish best option for them they shouldn't join like people should make the selfish best decision for them.

Otherwise, you do not have equilibrium.

The second we manipulate someone into joining us, we're [ __ ] up because we're not going to have retention.

They're going to realize that we were not earnest. So, we have to genuinely

not earnest. So, we have to genuinely just make superpower the best decision for someone joining.

>> Yeah. Is there any like very unusual things that you've done for one of the employees that you've brought on board in the past that's like way outside the bounds of what people normally do?

Not really because I think that you um start to set a precedent and it's really hard because future hires will anchor to that precedent. We are very generous

that precedent. We are very generous with equity. Um I think that if you can

with equity. Um I think that if you can genuinely find someone who can materially change enterprise value and you genuinely believe talent is exponentially distributed, you need to

overpay. And I think or not overpay but

overpay. And I think or not overpay but like pay a lot. And I think a lot of >> the whole founders podcast thing where you basically can't overpay for Steve Jobs working at Apple. Yeah. Totally.

You pay him $400 million to, you know, come rejoin and suddenly it's worth like a billion, you know, hundred billion dollars something.

>> Yeah.

>> And the best people realize this.

There's a reason Sam is paying $6 billion for Johnny. There's a reason Zach is giving $200 million salaries.

There's a reason Master Son paid Nikesh Aurora like $200 million a year and Nikesh ended up demanding a billion dollars a year in compensation.

So yes, talent is exponentially distributed and you need to pay up. And

today we're at our series A approaching our series B. Um if we found someone who we thought would completely change the trajectory of the company, we'd be happy to give them 5%. Like for the right

person, we would give them five. That

sounds crazy at series V, but it's worth it if you find the right person.

>> So, I I I know this this sounds almost exactly like what Steve Jobs has talked about where for the first like 10 people, you want to be even even more than like an investor, you know, bringing on an early investor, you basically want to ask yourself for every

single person, is this someone who is going to like materially impact the trajectory of the company or is there like any possibility that they detract and like just absolutely basically only hire people that you're willing to overpay and like you want to.

>> Yeah. you know.

>> Yeah. If we're overpaying, I'm so happy.

>> Yeah.

>> Because by conventional metrics >> because uh if talent is actually exponentially distributed, we're actually probably not overpaying because the world is so anchored to linear

thinking in terms of compensation. So if

we're overpaying, quote unquote, I'm very happy.

>> Yeah. Do you do you have any other examples of kind of understanding human biases? Like exponential thinking is a

biases? Like exponential thinking is a very unusual thing for human brains and even if you try to make yourself you know force yourself to think in that way

of you know 2 * 2 * 2 * 2 like it's very difficult um how do you do that for yourself >> I think that um there there's so I think

understanding the limitations of human the human brain is really powerful I love the Charlie Mer idea of um understand elementary psychology um when I was 18 years old after high school. I

didn't go to university. Instead, I took a learning gap year. And one of the ideas of that year was to understand all the foundational principles that in a way define the world, right? And in the

short term, the local optima is they become mental models and you reason from the principle and then over time they just become part of your way of thinking and you're combining ideas in novel ways to come up with a certain conclusion. I

think one example of flawed human thinking is the inability to properly understand exponentials. I think another

understand exponentials. I think another is probably overindexing on logic. Um I

think that we are trained to just use logic. Good luck being in a job and your

logic. Good luck being in a job and your boss asks you, "How did you come up with the answer?" You're like, "It feels

the answer?" You're like, "It feels right."

right." >> Yeah.

>> It's it's surprising. It's surprising

how much actually comes down to like vibes. And then properly training your

vibes. And then properly training your intuition on what what does good look like and then just understanding just through that training of your intuition when you see it, you know it, but you

can't exactly explain it. All of my team will will laugh because I use the word vibes often and they're like, "Why do you think this?" And I'm just like, "Vibes?" And I will intentionally say

"Vibes?" And I will intentionally say that because so often we make a decision and we try to justify it retroactively using logic. Yeah.

using logic. Yeah.

>> And we don't realize we're doing that.

And I try to be very cognizant of when I'm doing that. And instead of trying to justify it retroactively, I'll just say vibes. And then because people are not

vibes. And then because people are not happy with vibes, I'm like, "Cool, I'll give you the logical answer." And then I'm like, "I promise you this is not the actual logic, but it'll make you happy."

Well, what's what's funny is like fives is actually I so the whole like logic thing a lot of people make decisions I mean I think this is just like a normal human thing where you'll make a decision and they'll try to justify it because if

you just say like I did it because I felt like it it's not a good answer like no one wants that they want a reason for doing they want the why right so you just create the why out of thin air even though the why isn't really there um and

it is kind of there but like for for intuition you're >> you're taking an action based on a bunch of information that you have and you don't necessarily know every single process that your brain goes through to

feel the way about a decision that you're making.

>> Um, anyway, >> I think people at the top and bottom both use intuition and that means it's hard for someone to say using intuition is a good thing because some people at the bottom also are just using vibes.

>> But then you get to the top and um George Soros's son was asked, "How did George know when to sell?" and his son said, uh, George would wake up like an itch in his back thinking about a

company and then he would sell. Right?

If you look at master son, he uses vibes. Most of the people at the top

vibes. Most of the people at the top will use intuition. Um, but they have earned the right uh to do that because they have proven over an extended period of time that their intuition is correct.

In other words, they have a high believability weight on their intuition.

And um the strong empirical view, my strong empirical belief here will say even if I disagree with someone, if they have a high believability weight on a certain decision, because empirically

they made that decision right in the in in the past, I will trust them even if the first principles are disagree.

>> Yeah. It's a lot like I mean if if you ask Warren Buffett or Charlie Mer to like look at a balance sheet or look at a company, they can probably within like a few seconds know whether or not they want to invest in it just because they've looked at so many companies. How

many or how do you think about building a really solid foundation for intuition and yourself?

>> I think a big part of it is seeing a lot, being obsessed with information, seeing a lot, learning a lot, reading a lot, putting yourself in a lot of situations, taking a lot of action,

getting a lot of reps in. Like I

mentioned, I took a learning gap year that year. I went to conferences where

that year. I went to conferences where the average age in the room was probably 45. And I would put my hand up and be

45. And I would put my hand up and be like, "Hey, I'm 18 years old and I'm taking a learning gap year. what's your

advice for me? I'd have all sorts of conversations with the older people. I

just like get as many reps as possible per unit time. I think in many ways intuition is access to experience stored in subconscious.

I think the second thing is being very aware of what is coming up in your body, right? I think a lot of people have like

right? I think a lot of people have like blunted their ability to intercept or feel what is happening in their body.

Um, but it is something we have. Animals

have some animal all animals have intuition and instinct. Some have

emotion. Only humans have logic and we've used logic to get in the way of everything else. So when I see for

everything else. So when I see for example a design or I see something rather than asking myself do I think this is good I ask myself how does this feel in my body? You we we saw each

other yesterday. I was in a plant shop

other yesterday. I was in a plant shop and and you asked me which plants are you deciding to buy? I'm like just the ones that feel right. and you understood that as like a viva thing, but actually what I was trying to say is there's some

logical process that is happening, but I want to notice the emotional feeling that comes up around a certain thing.

And so that's the second thing, being aware of what's coming up in your body.

And then the third thing is paying attention over time to where your intuition is correct and incorrect to understand where you have a high believability weight. For example, I've

believability weight. For example, I've got a very high believability weight on talent. I over time have not made many

talent. I over time have not made many wrong talent decisions and I made many contrarian talent decisions which have turned out to be correct but I have a low believability rate on something like

a Facebook ad. I don't think I have a good intuition for the kind of Facebook ad that performs well whereas someone in our team has a far better intuition and therefore even if I disagree with their decision on the Facebook ad I'm like

you're at a high higher believability weight than me. I'm just going to trust you on that one.

>> Interesting. Okay. Yeah. Uh, how do you uh think so? You've got like I think you said 16 founders. Is it 16 founders on the team?

>> Yeah, 15 founders on the team.

>> 15 founders on the team. How do you think about >> not 15 co-founders with no 15 people on the team are former founders >> that have previously built >> six of them are former YC founders and

more than half of these founders have had reasonable exits. Not billion dollar exits, but like reasonable exits.

>> Yeah. How do you how do you attract those types of people? And like in your in your mind when you're going through the kind of reasons for you know who to hire? What what what about a former

hire? What what what about a former founder is super attractive to you?

>> So there are two kinds of people we try to hire. Um one is someone who is best

to hire. Um one is someone who is best or second best in the world at solving a certain thing. And again, similar to

certain thing. And again, similar to what I said before, which is when you fix the assumption you need to be a billion dollar company in three years, you make decisions to make that come to reality. The same happens here. When you

reality. The same happens here. When you

fix the assumption that you need to hire the best or second best person in the world, you start to only look for those people. And it's very easy to just say

people. And it's very easy to just say no to everyone else. So that's the first kind of person we will hire. The second

kind of person we will hire is someone who per unit time has done more than just about anyone else and anyone else on Earth. And this person typically

on Earth. And this person typically looks like a 19, 20, 21 year old who is absolutely brilliant, absolutely cracked 3 to four sigma worth work work ethic,

three to three three to four sigma IQ, three sigma creativity. Like they're

just like really brilliant people. I

call them spiky people. They're people

who have done things that are not just at the very pinnacle of what they could have done, but also done that in an idiosyncratic way. It's kind of an

idiosyncratic way. It's kind of an idiosyncratic way. So there are two

idiosyncratic way. So there are two kinds of people that I think companies should hire. Best or second best in the

should hire. Best or second best in the world or like a very spiky young person.

The very spiky young person will end up exceeding best or second best person in the world. The very spiky young

the world. The very spiky young >> because a very spiky young person um when I say best or second best in the world, I mean as an operator at solving a specific business function, right?

Whereas the spiky young person by the time they're the age, by the time they're 35 or 40, they're going to be starting their own multiple billion dollar company, right? Like I think we have probably 5 to 10 young people in

our team who will start billion dollar companies. The catch is they're like 19

companies. The catch is they're like 19 today or 20 today. And their growth curves are absolutely wild. And I

believe in this idea of radical empowerment which is you give them way more empowerment than they quote unquote deserve. Even if they can't do the thing

deserve. Even if they can't do the thing yet, you have to empower them because they will grow into that role and exceed the expectation that existed for that

role very quickly. So that's the kinds of people to hire. Going back to how to persuade these people to join the team, I think a couple of things have to be true. One is you need to be working on

true. One is you need to be working on something that actually matters for humanity, right? That actually pushes

humanity, right? That actually pushes the world forward.

>> Yeah.

>> The best people want to work on a mission that matters.

>> The second thing is you need to work on something that can be a trillion dollar company and has a reasonably clear path to being a hundred billion dollar company.

The third thing is you need to also have a very clear path to being a billion-dollar company in the next couple of years. So you see how several of the beliefs I had before now completely change your ability to hire.

And because you can now change your ability to hire, you can actually make those things come to life.

>> Yeah, >> that's probably the the third thing. The

fourth thing is I think being able to art being able to allows them to understand the the mission and the vision and the potential through brand and marketing is really

important. Right? A lot of our initial

important. Right? A lot of our initial marketing and branding wasn't actually targeted at customer acquisition. It was

targeted at talent acquisition. Right?

We focus intentionally on Silicon Valley or on talent clusters because our belief was we're not going to build the world's best company by having 5,000 customers versus 3,000 customers in the early

days, but we will by having the best people on Earth.

>> Do you feel like the brand has been more than just so the brand initially is actually not targeting the customers all, it's just targeting investors and hiring and like people that want to potentially partner with you.

>> Um, it's it's both. If I look at the initial website, that was a [ __ ] website for conversion, right? But it was like cool and because it was distinctive, it was useful for talent and capital acquisition more so than customer

acquisition. We've now changed that and

acquisition. We've now changed that and it's rotated into a customer acquisition website, which is completely different.

But yeah, that that was true in the early days. I think the next thing you

early days. I think the next thing you need to do to hire these great people is just be really good at selling them.

Right? I actually think that sales is also highly convex. um where a great salesperson is a thousand times better than just a good salesperson. And I used to a year ago think I was good at sales.

I realized that I was really [ __ ] back then. I'm a little bit better better at

then. I'm a little bit better better at it now and in a year I'm probably going to realize I'm really [ __ ] now. Um so

being good at selling people is important. And that means deeply

important. And that means deeply understanding what they want, right?

being able to communicate and construct that and then creating a sales process to educate someone on why this is going to get them what they want more effectively than anything else. What was

your process a year ago and what have you like shifted or evolved since then?

the best sales. Well, when I'm around an

best sales. Well, when I'm around an elite salesperson, I'll chat with the person for 30 minutes about something that's not the company and I will leave

that conversation thinking, "Holy [ __ ] this company's going to be a trillion dollar company, but we haven't chatted about the company." In other words, the best sales doesn't even feel like sales.

>> Yeah. And the best sales is often about planting a vision in someone's mind rather than just stepping through all the logic, right? Elon does this so

well. He says so so so little, but

well. He says so so so little, but you're left with this feeling of this can be huge. Self-driving autonomous

robots. He says so little, but he just anchors the vision in your mind such that you can imagine it being huge.

That's one view. The other view is the complete opposite which is actually do hardcore very obvious in-your-face sales. And the way I learned this was I

sales. And the way I learned this was I was chatting with someone who was debating between joining Apple Design Lab or Rev, which is Mike Spiser and Syill Ventures new company. Mike has

incubated many unicorns, Snowflake amongst others. And I asked this person,

amongst others. And I asked this person, why did you decide to join Rev versus Apple Design Lab? And he said, well uh Mike uh sat me down and we chatted for

two hours. And Mike basically said, "I'm

two hours. And Mike basically said, "I'm going to sell to you for 2 hours and tell you why joining us is by far the best decision." And he's like, "Mike did

best decision." And he's like, "Mike did not let me leave that conversation until I said I was joining." And he literally, I'm just going to like hardcore sell you. And sometimes I'll do the subtle

you. And sometimes I'll do the subtle sales. Sometimes I'll literally say to

sales. Sometimes I'll literally say to someone, "Look, I genuinely think this is the best decision for you to join us.

I'm just going to sell you." And I just keep going and going and going and going until they join. And it surprisingly works. So being like uh so just being

works. So being like uh so just being like extremely transparent about like here's what I'm doing and I know that I'm going to I know that I want you to make the right decision and I'm just going to keep on working until you make that right decision.

>> Yeah. I can't sell someone unless I genuinely believe it's the right dec.

Like there have been times I'm like this is not the right decision for you.

>> But if I genuinely believe look you're smart, you're logical. I'm just going to share all of my thinking around why all the other options are kind of stupid and this is the best decision for you. And

I'll say I'm probably a bit biased like like I have a lot of I'm probably a bit biased. I'm just going to share and I

biased. I'm just going to share and I just do that.

>> Another Charlie Munger quote is like uh you're smart and I'm right and eventually you're going to figure out that I'm right.

>> I [ __ ] love that.

>> Yeah. How do you think about incentives?

>> I think that you can predict most behavior by incentives particularly in the US. I think that the higher the

the US. I think that the higher the individualism of any system, the more incentives matter. I remember moving to

incentives matter. I remember moving to the US and I would often have people ask me, "How do you seem to know so much about the US healthare system? You just

moved here." I'm like, "It's pretty easy. I only need to know one thing,

easy. I only need to know one thing, which is how does money flow?" And I'm I'm not exaggerating. I'm not being facitious here. If all you know about

facitious here. If all you know about the US healthare system is how does money flow, you can predict most outcomes. You can predict um why certain

outcomes. You can predict um why certain things are the way they are. Often when

I see something that is seemingly irrational or sub-optimal, the first thing my mind goes to is but what's the incentive, right? Because there's nearly

incentive, right? Because there's nearly always some sort of incentive that describes a certain behavior.

>> Can you walk through the incentives of like the current healthare system and like how hopefully this is going to change that?

>> So in the US uh 20% of GDP is spent on healthcare and life expectancy is going backwards. If you look at uh the most

backwards. If you look at uh the most OECD countries around 7 to 10% of GDP is spent on healthcare and life expectancy is going up. So we conclude empirically

that the US healthare systems are really [ __ ] up. Okay cool. Well let's dive a little bit into the incentives. So uh

under the affordable care act the margins of health systems are regulatory fixed. The second your margin is fixed,

fixed. The second your margin is fixed, the only way to increase revenue is to increase costs. So how's that for? Guess

increase costs. So how's that for? Guess

what costs are going to do, right? The

way most hospitals make their money are procedures and pharmaceuticals. So if

you go to a hospital, guess what's going to happen? Lots of procedures and lots

to happen? Lots of procedures and lots of pharmaceuticals, right? Um the largest companies in

right? Um the largest companies in healthcare are pharmaceutical companies.

Um, so, uh, there some of the largest donors are pharmaceutical companies. So,

guess what? Pharmaceuticals are quite pervasive. I love this articulation of

pervasive. I love this articulation of pharma companies as as, uh, law firms with biotech interests, right? That's

like fundamentally what they are. Um, so

all sorts of these like weird incentives throughout the healthare system, the result in something which is very much a like local optima. Even if you look at peptides, which we were injecting

ourselves with earlier, many of these compounds have been around for 10 to 20 years, >> but because they're naturally occurring in the human body and because they've been around for a while, pharma cannot pass it to them. Because farmer can't

patent them, farmer can't make much money from them. Because farmer can't make much money from them, there's no submission to the FDA that results in them being legalized.

>> Right? Um, now pharma all of a sudden discovered that you could take a GLP-1 and you could change the amino acid chain ever so slightly and you could create semiglutide aka zmpic and you

could patent it and all of a sudden a GLP-1 which has been around since the 2000 like '9s is like this blockbuster drug because there was an incentive and farmer could patent it, right? So there

are a couple of the incentives that exist in in the US healthcare system.

There are all sorts of perverse pricing models with like with like middle people who get this kickback and that kickback.

Um there's this meme in healthcare which is like no you can't do kickbacks in healthcare. It's like full and like the

healthcare. It's like full and like the entire [ __ ] system is structured by kickbacks that aren't aren't called uh kickbacks.

>> They have special names.

>> Yeah. There's all sorts of like like this is like literally this is a specialty drug and because this is a specialty drug the way we price it is is like kind of different. Anyway,

>> with anyone that's really good, uh the mental models don't just like happen overnight. And so you don't just

overnight. And so you don't just immediately wake up one morning and say, I should, you know, only optimize for like a hundred billion dollar outcome or be more ambitious or whatever. Um can

you talk about like what was the first company that you started and like what was the thinking behind doing that?

>> The the two companies I started around the same time. One is I would uh sell fake [ __ ] on the playground at school when I was I think eight or nine years old.

>> For example, there was this trend of power bands. They were these rubber

power bands. They were these rubber bands that you could put on your wrist and apparently they would allow you to jump higher and be more sporty. And they

were selling in stores for around $70.

So I went to Alibaba. I think this is in 2012 or 20 2010. I went to Alibaba and I bought several hundred of these power bands and I sold them for $5 in the

playground and I would say to people um uh the more of these you have the the better the effect. So you need as many of them as possible and that was kind of

business number one on the playground.

The second was I was playing Minecraft um at the time. I who used to love it as a game and uh I was played on a large like several 10 like maybe 50,000 person

server and there was a leaderboard that ranked people by wealth like well I want to be the richest person on this server.

So I set myself the goal of being the richest person on the server and that's pretty hard. It's basically a a a

pretty hard. It's basically a a a mirror of the economy. It functions like the real world like the real economy.

there are lots of like 40-year-old very smart people who spend a lot of time trying to be the richest person on the server and I became the richest person and at the time I didn't think much of

it um but in retrospect the exact kind of actions that were taken in that world I could have taken in the real world the only difference is in the real world as a kid you're not allowed to do that stuff you're not meant to be able to do

that stuff you can't think about this stuff right whereas in that game world it was just a game anyway once I was the the wealthiest on the server. I had

local status in that community. So I

started my own server. Um started

monetizing that, made some money from that and that was uh kind of happening at the same time.

>> Yeah. Did you did you have a like a few year pause in between starting the you know doing the Minecraft server, doing the power bands um and then starting like the next company or what happened

during like a high school years?

>> Yeah, I didn't start any company in my high school years.

>> You know why? Um,

I don't know why. No, it's strange. I

think I think I probably became too perfectionistic and too high fear.

>> I think when I was doing that stuff when I was younger, I had zero fear. I think

I was that idea of just like a child playing around. I hadn't internalized

playing around. I hadn't internalized dogma. I hadn't been told this is what

dogma. I hadn't been told this is what you can or can't do. It's like I can just do whatever. Whereas I suspect in high school there's probably a combination of of internalizing more

fear. Probably a pressure to uh be cool

fear. Probably a pressure to uh be cool or like fit in. Um and I I to conform and I didn't feel like I was as authentic. Instead, social pressure held

authentic. Instead, social pressure held more weight. I think I started playing

more weight. I think I started playing more conventional games. I'm like, well, I want to top every subject I do. I want

to be the captain or be be one of the best people at all the sports I'm playing. So I think I played a lot of

playing. So I think I played a lot of those conventional games and that takes time particularly if you're doing it across most kinds of of achievements that maybe played into it.

>> Was there a different version of Max for let's say like a few years where you were trying to kind of go down the you know pre-built path cuz it kind of looked like you were doing that you know

you go to high school and then you go to law school or college or whatever and then you decide to opt out at some point. How how did you how was your

point. How how did you how was your thinking during those few years that you were going kind of going down the traditional path?

>> Yeah, I think I think uh I definitely did to an extent and it felt very non-authentic. Um so I took the learning

non-authentic. Um so I took the learning gap year I mentioned and that was deeply authentic. I started some small

authentic. I started some small businesses. I learned about a lot of

businesses. I learned about a lot of things. I

things. I >> What types of small businesses?

>> Uh like agency kind of businesses not nothing that meaningful. I started a company that still operates today called Next Chapter which is basically a community for the most talented young people around the world and the talent

basically Teal Fellows before Teal Fellows. The talent bar in there is

Fellows. The talent bar in there is absolutely brilliant. I think most

absolutely brilliant. I think most people in there are going to start billion dollar companies which is really cool and my brother's now the CEO of that business and he started all sorts of businesses that come out of that that

actually make cash a dirty word in Silicon Valley. Um um and yeah, I did a

Silicon Valley. Um um and yeah, I did a little bit of the conventional path. Um

uh those conventional things and I think that was potentially a productive environment. Um I didn't really know the

environment. Um I didn't really know the US was a thing. The idea of going to a US college was not in the set of options. No one around me had ever done

options. No one around me had ever done that. And in retrospect, going back in

that. And in retrospect, going back in time, I would have moved to the US at 18 um rather than 22. Um, and honestly, I think that single decision probably would have had the most impact on my

life. If I could go back and change one

life. If I could go back and change one thing, it would have been that decision.

But we live and we learn. I remember I was listening to to like Sam Alton the other day and he was talking about how he played that conventional game. I'm

like, "What? He seems like such a startup bro." I say, "No, you play those

startup bro." I say, "No, you play those games for a bit." But I I tapped out of them pretty quickly and I did think of them as stepping stones, too. So, we did the law thing. I came first in my first year of law at Australia's top law

school. I dropped out. I after only one

school. I dropped out. I after only one year of university interned at Goldman Sachs and like that's weird to do after one year of university and then I spend a couple of months there and then I'm like [ __ ] this.

>> What I find funny about the Goldman Sachs story is that that was actually Sam's like that's where he was going to go. It was either Y Combinator or

go. It was either Y Combinator or Goldman Sachs and he like did I think like a few interviews at Goldman and like was going to have a job but then he just decided to get on a plane and fly out to Silicon Valley even though Paul

Graham said like don't do it.

>> Yeah. Yep. One of your goals is you want to help people like I have I sleep in my optimal state. I'm sleeping for 10 hours

optimal state. I'm sleeping for 10 hours a night between like 10 uh 10 p.m. and 8

a.m. the next morning um every night. I

love that sadly. I travel a bunch so I don't get to do it all the time. Um but

one of your goals is to basically get people from like 8 hours of sleep down to 5 hours of sleep but rested. You

know, you feel rested when you wake up.

How is that possible? What levers can you pull on to actually make that happen? So this comes from two

happen? So this comes from two questions. One is how do we maximize

questions. One is how do we maximize productivity and human output with the belief that there's increasing returns per marginal unit of time. Again it's

convex rather than concave. And the

second belief this comes from is this idea of how do we actually extend human life. And if you look at the 60 billion

life. And if you look at the 60 billion people to ever live on Earth, no one's lived past 150. Just about no one has lived past 120. It's very very very rare. So one thing we can try to do is

rare. So one thing we can try to do is we can try to add years to the end of life. But the other thing we know is

life. But the other thing we know is that of 60 billion people live on Earth, millions have had genes that allow them to sleep 4 hours a night or 3 hours a

night and live the same, have be cognitively just as performant, be physically just as performant, feel the same. So I'm like, okay, well, of these

same. So I'm like, okay, well, of these two pathways to extend lifespan, which was more reliable? Modifying genes to do something we know that millions of people have done of doing something that's never ever been seen in human biology. I'm like, well, probably the

biology. I'm like, well, probably the sleep one, right? And if you do this, you actually add around 15 years to someone's life. And you don't add that

someone's life. And you don't add that to the end of someone's life. You add it just through someone's life.

>> So I think it's actually one of the most reliable ways to increase lifespan. The

other reason I I love this idea is I just want to spend more time awake. I I

I'm quite obsessed with productivity and I think this is one way you can be more productive. When I was younger, I wanted

productive. When I was younger, I wanted to learn to lucid dream and like most people want to learn to lucid dream to like fly and have sex. My like thinking was I want to learn to lucid dream so I can like learn more. So, I just want to

be like productive when I sleep. Um,

because it just feels like a waste to spend 8 hours in bed at night. So, I

love all of those different devices that are trying to either compress sleep or enhance lucidity and allow you to actually do things in your dream state.

>> Yeah. What what what products have you tried to use? I know that you talked about like you used the ALE for what was it like a few nights or before deciding to return it. What other products have you tried to try to pull on the lever to

improve things?

>> Yeah. Yeah. So, from the age of uh 17 to 20, I used to wear a headband um that would actively improve my sleep and my deep sleep percentage went up and I could sleep fewer hours and still feel the same.

>> And that would basically play um subaudible sounds via bone conduction to hold you in deep sleep longer. And that

company was discontinued for a bunch of reasons. Um some say the science didn't

reasons. Um some say the science didn't work. Subjectively, I felt it was

work. Subjectively, I felt it was effective. So, I tried that. I've tried

effective. So, I tried that. I've tried

pulse EMF, which is a device you can wear on you. I've tried other headbands that actively improve sleep. I've tried

all sorts of different supplements. I've

tried the lucid dreaming thing. I

suspect the only I' I've tried certain peptides. So, um,

Epailon um, has a positive effect on sleep for me in particular.

I think that likely we're going to need to find a path to solve this problem through genomics.

either by editing the genome I think that will be a reliable path in time but it's unsafe right now crisper isn't perfect it's also illegal um so we'll probably see the application happen

first in China or in the US in the military rather than so I think genomic editing the other thing that's interesting is looking at of the people who have the gene that encodes for the phenotype of short sleeping what

chemicals are they expressing or what is actually occurring in the body and can we like introduce yeah can we introduce some sort of molecule that signals to

the body to have that effect for example we can introduce a peptide into the body that signals to the body to produce a rexin um which is one of the things that

is over uh produced in short sleepers and maybe that induces wakefulness and allows people to sleep for short I don't know but I think these are like the interesting things to play around with

>> interesting okay um for you yourself right now when you're thinking through all the things that you can be doing at any given moment. Uh what is the highest leverage lever that you kind of think most of the time that you're

pulling on?

>> It's different at different points in time. Right now it's getting the company

time. Right now it's getting the company to obsess over revenue. The reality is we have an amazing team. We have a product that is great for this specific

stage we're at. We have a very clear strategy and strong hypothesis in the market. Um, we need a lot of revenue to

market. Um, we need a lot of revenue to bring in the capital required to build the next stage of the company, right? We

also need a lot of revenue because that's correlated with the number of customers we have and that allows us to get data to build the AI doctor, which is like the long-term vision of where we're getting to. So right now it's like

how do we how do I create a system that uh people can operate in that allows them to effectively drive revenue and how do we create a culture internally that results in things being prioritized

that result in revenue. Now at different stages there are different things. A

month ago the number one most important thing for me was hiring. So we have three best in world people we're trying to find how do I find the best person in the world and that meant literally saying here are the 30 companies that

done this best. let me chat with the key person at every single one of those companies. Say this person is the best

companies. Say this person is the best of all of them. Let's try to hire that person. And that was the biggest lever.

person. And that was the biggest lever.

Um in 4 months from now, the biggest lever is probably going to be capital.

It's probably going to be fundraising.

Um so it changes at different points in time. And I'm very obsessed with this

time. And I'm very obsessed with this idea of what is the core constraint right now. And I think there's a

right now. And I think there's a tendency to look do a million different things and say this is important and this is I'm like yeah, they're all important. And my job is to say none of

important. And my job is to say none of them are as important as the single most important thing. So how can I say no to

important thing. So how can I say no to most things but the single most important thing?

>> Interesting. Yeah. And so does that kind of translate uh to the same way like how do you think about learning? you for

myself, I typically if I want the result of someone else or, you know, if I want to, you know, create something specific, I'll go to the person that I look up to the most in that like if I want to be a billionaire or build a massive company,

you just go to the people that have actually done it and then listen to what they say, right? How how do you think about learning in that way?

>> I think learning there's different kinds of learning that are necessary to solve a certain constraint. When I was 19 taking the learning gap year, the most important thing I think to learn was one

learning how to learn, right? That's a

meta skill that improves the acquisition of every other skill and two was learning foundational principles, foundational microeconomics, foundational macroeconomics, evolutionary evolutionary biology, um

fundamental psychology, etc. And then there was a point in time where the useful learning for me was um uh deeply understanding the the US healthcare system and how that worked. And that

meant working as a receptionist in a [ __ ] doctor's clinic, um, investing in a lot of health companies, reading medical textbooks. I read like four

medical textbooks. I read like four textbooks in the span of a week. Um,

then there was a point in time where the most productive way to learn was chatting with people who had done it before at the pinnacle. Then there was a point in time where the most productive way to learn was just taking action.

Like literally done take maximum action. And now the most productive way to learn is probably two things for me. One is finding very very

smart first principles thinkers and having debate. Having debate and

having debate. Having debate and discussion that's often slightly philosophical in nature. I think I find that that really pushes thinking forward. And the other most valuable to

forward. And the other most valuable to learn is just like being by myself like taking walks in nature doing something deeply introspective deeply thoughtful.

Um because I think that I'm probably at the point now where the important ideas are unknown ideas and if I can induce my

brain to recognize that thing um then then that that's that's powerful. Yeah,

that's that's interesting. Uh how do you think about you mentioned that you want more like beautiful products and you want more like beauty in the world. How

do you think about creating something like that or why more people don't?

>> I have this thing which is my my north star is build beautiful things physical and digital that that improve the world and this is just something that's

personal to me. I I believe that um a founder in many respects is an artist and the the act of art is the act of creation and it's uh partially an act of

selfish creation which is I derive joy from this thing and then it's a partially an act of altruistic creation which is beauty actually changes human psychology and behavior and how we feel in the world right there's a reason

people like the feeling and emotions that come from walking through nature because there's beauty in nature it's all in the golden ratio there's lots of micro things that nature has optimized over time to result in what we call

beauty. Um, and then I modify that by

beauty. Um, and then I modify that by saying things physical and digital and it's my belief that we're going to see this movement from from the cloud to the ground or the things that are going to really matter over the next decade are

things that are more physical in nature, right? Software is kind of commoditized

right? Software is kind of commoditized code writes code. Um, and to actually change the world, we need to interface with the physical world. Um so I think

about things that modify the physical world as well. Um when two and a half years ago in deciding what I wanted to spend the next 30 40 50 years on uh there were two things that I deeply

cared about. One was building a new

cared about. One was building a new healthare system and the other was building a new city and they were the things that were personally meaningful to me. I thought mattered for humanity

to me. I thought mattered for humanity and could support really generational companies.

>> Why why the city?

>> I think that building a new city allows you to solve so many things in concert.

You solve for health, you solve for innovation, you solve for education, you solve for culture. I think at the same time, there aren't many great cities.

There's actually no city I really love in the US. They all have different flaws. I think at the same time, you can

flaws. I think at the same time, you can create a new city that leverages the network effect of an existing city because of fast transportation. So, I

hate the idea of let's create a city in the middle of like bum [ __ ] nowhere in the Mediterranean. I don't think it

the Mediterranean. I don't think it works because you need to kickstart the network again. What is possible is

network again. What is possible is creating a city between SF and LA connected to both via Hyperloop. Now you

can get to both in maybe 10 minutes. So

you can inherit the network effects of those cities. But then this city can

those cities. But then this city can maybe have a special economic zone. It

can be structured to support innovation, happiness, health, culture. Uh and it's very hard to modify that much about the world without actually modifying the the physical environment which is the city.

Um I think cities are some of the greatest business models of all time.

The UAE is in many respects like a combination of cities. Singapore is a city. What they're doing with the line

city. What they're doing with the line is a way to neon that big project is a way to diversify away from the oil economy by creating a city. Um then it's something that's been deeply personally meaningful. The first job I ever wanted

meaningful. The first job I ever wanted was to be like an architect, right? I

love this idea of expressing visual taste into the world um like in the most physical way possible which is through city building. And the final thing is I

city building. And the final thing is I think this is very robust to AGI. I

asked the question often of assume AGI is here. What does this imply about the

is here. What does this imply about the world? Right? And if you assume AGI is

world? Right? And if you assume AGI is here, most companies are actually irrelevant, right? I think two things

irrelevant, right? I think two things that still matter are like human health and the physical environment which we exist in aka cities.

>> Why did you decide to kind of put that off and and focus on the health angle?

>> The health system has to happen now.

>> Um I just think that we're at a pivotal like turning point. Is it also more like of an impact perspective? You can have a bigger impact on like a billion people versus a city is you know maximum of a

few million people I assume.

>> Yeah. I I think the city can have a big impact because derivative impact which is what are the people in the city do right? If you actually create a

right? If you actually create a foundation that allows for more innovation that has a big derivative impact. So it's probably less the impact

impact. So it's probably less the impact standpoint. It's more like what matters

standpoint. It's more like what matters right now. Like right now we're at this

right now. Like right now we're at this turning point where we can see a new health system emerge. we can see a health system before the health system emerged. We're going to have AI doctors,

emerged. We're going to have AI doctors, right? Again, health is a platform

right? Again, health is a platform solution because if you solve for people's health and you and the idea of solving for health isn't just preventing disease. That will be table stakes.

disease. That will be table stakes.

Solving for health is enhancing human capability. If we actually enhance human

capability. If we actually enhance human capability, that also is a platform that results in derivative impact. The people

whose capabilities enhance now do more things. Um so that was part of it. Um

things. Um so that was part of it. Um

that that was like the timing component.

The other part of it is like what is more possible for me right now. For me

right now, it's more possible to start a new healthare system than to start a new city. I think that the healthare system

city. I think that the healthare system one can compound faster. I believe that the new city one will still be a problem that can be solved in 30 years time, right? It's hard to predict because of

right? It's hard to predict because of AGI, but I do think that problem will still exist in 30 years time. And I

think going into it with like like hundreds of billions is again I'm making assumptions. It's like easier than going

assumptions. It's like easier than going into it um um from scratch. Is it also probably easier from a perspective of like you have this track record of successfully building something in the form of a company thus more people will

trust you when you're trying to build this new thing?

>> Yeah. Like I look I might change uh look for most of my life there's been two things I've cared a lot about which is health, human potential, productivity, what we can do and the physical world

and environments. So that might be true

and environments. So that might be true in 30 to 40 years time but there's a world I get like it's 2008. I'm like,

actually, I don't care about building a city anymore. That problem solved. So,

city anymore. That problem solved. So,

it's just so hard to predict 50 years in advance. I do think though, what I can

advance. I do think though, what I can understand is what what are some of the problems that I think are going to be the most important and health and the physical environment are some of them.

>> So, like a few months ago, I started taking a big old regimen of, you know, seven different pills in the morning and like a powder with creatine and all these all these different things. And I

noticed not only was like motivation to do productive things just massively improved, but I also did become somewhat smarter. Um I know that you focus on

smarter. Um I know that you focus on trying to kind of systematically improve IQ. Uh what are the biggest things that

IQ. Uh what are the biggest things that we can or that you can focus on uh to improve IQ?

>> So I think most things most great things that have been created in the world can be explained by people who simultaneously have two traits. One is

high IQ and two is low fear, right? You

need to be at least three sigma on both.

And the catch is they're inversely related. So there are very very very few

related. So there are very very very few people on earth who are three sigma IQ and three sigma lack of fear. I think

both of these things are also very malleable. Right? So as a result I try

malleable. Right? So as a result I try to systemically do things that improve IQ. Um, and I will because I've tried to

IQ. Um, and I will because I've tried to develop interception over the years, sometimes be sitting there and I'll be like, I can't solve this problem at my level of IQ. I need an extra five IQ points. And I will do something that

points. And I will do something that gives me an extra five IQ points. It

might be like CAX or Salank, which are like nasal sprays for cognition. It

might be that nicotine is the kind of IQ I need. It might be that I need like

I need. It might be that I need like completely lateral thinking and I need to do something else. Um, it might just be sleep, right? Um, but I will try to have a sense of here's a problem that I

can't quite solve. Let me increase IQ and solve it. Um, and I will use some sort of compound that in increases IQ in the direction I want to allow me to

effectively solve a problem. Um, and

it's really weird. It's almost like I used to I used to study mathematics, right? And sometimes when you're in a

right? And sometimes when you're in a high IQ state, the solution just comes to you. It's this amazing feeling of I

to you. It's this amazing feeling of I didn't do anything. It's just like here.

It's the whole like I just you know how did you come up with this equation? I it

like came to me in a dream.

>> Like it's it's the weirdest feeling but when your IQ is high enough and my IQ is not always I have this sense of when I IQ's high and low um the solution just comes to you and that's not just for a

math problem that's for like any problem in the world and you make better decisions and what we can do is a function of set of decisions we have made. Um so I do think about

made. Um so I do think about systemically increasing IQ. Okay, let's

let's end it on like what's the hardest thing you've overcome?

>> When I moved to the US in 2022, um I was broke. I had no money in my bank account. I was sleeping on the

bank account. I was sleeping on the floor of a friend's apartment. No one

gave a [ __ ] about who I was. I was just some random person in Silicon Valley. It

was impossible to meet anyone, to meet investors. The only people who cared

investors. The only people who cared were actually, ironically, the smartest and most talented people. Like the

people at the top gave me some light of day and everyone else was like, "No, we're just a signal monkey and you don't have enough signals yet. Show me your $5 million or $10 million fund raise and then we'll care." Um, at the same time,

I had a lot of beliefs about the future in the world that everyone disagreed with. I was strongly of the view there

with. I was strongly of the view there was a big gap between the best of care and what most people have had access to and all the doctors like, "What are you talking about? Quality is fine." I had

talking about? Quality is fine." I had this very strong belief that AI was going to far outperform doctors. And

again, this was before Chat GBT had come out. So I was like, "No, this is

out. So I was like, "No, this is [ __ ] What about the human art of medicine? What are you talking about?" I

medicine? What are you talking about?" I

had this strong belief that people would care about health. And again, the insiders were like, "No, people don't care about health until they're like deathly sick." And I had all of these

deathly sick." And I had all of these beliefs that everyone told me were wrong. At the same time, I I I like had

wrong. At the same time, I I I like had zero leverage, very very little money in my accounts. I just gotten out of a

my accounts. I just gotten out of a really tough relationship where I was like kind of bullied and the world felt really really tough. Everyone was like go back to go up at Sachs or go get a

job here. Um your life's kind of crumb.

job here. Um your life's kind of crumb.

There's so few people who actually believed and that is hard right to push through when no one believes and to hold beliefs that everyone thinks are wrong

is really really really hard. And I see this pattern in so many founders which is the the storm before the calm, right?

It happens all the time where there's this low people go through. And now when I see a founder going through that, I see my job as giving them belief and support because I've seen the pattern so many times, the storm before the calm,

the low where everything looks like it's going to [ __ ] and no one believes and everyone starts rejecting that person and not listening to that person and then they come up the other side of the J curve. So that that was that was a

J curve. So that that was that was a tougher moment over the past few years.

>> Interesting. Has there has there been any moment this might have been at Goldman Sachs or or somewhere else where you just felt like you were definitely moving in the wrong direction?

>> Not really.

>> Not really.

>> I've always been very intentional with the decisions I made. Even with the Goldman thing, I was like, I'm going to be here 3 to 6 months. I'm going to leave. And as a result, like one of the

leave. And as a result, like one of the most fun 3 to 6 months. Like, yeah, I was working 110 hour weeks. It was so [ __ ] fun because I was learning so much, right? I think it probably helped

much, right? I think it probably helped that I I knew how to how to break out.

Um, so no, not really. I think I've been quite intentional with the the decisions um that I've made.